Smrcka, Alan V.: search on Z-Library

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1

Targeting G protein-coupled receptor signalling by blocking G proteins

Campbell, Adrian P., Smrcka, Alan V.

Journal:

Nature Reviews Drug Discovery

Year:

2018

Language:

english

File:

PDF, 736 KB

english, 2018

2

Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy

Zhang, Lianghui, Malik, Sundeep, Pang, Jinjiang, Wang, Huan, Park, Keigan M., Yule, David I., Blaxall, Burns C., Smrcka, Alan V.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

3

Nucleoside Triphosphatases in Energy Transduction, Cellular Regulation and Information Transfer in Biological Systems || Hormone Signalling via G-Protein: Regulation of Phosphatidylinositol 4,5-bisphosphate Hydrolysis by Gq[and Discussion]

Paul C. Sternweis, Alan V. Smrcka, Stephen Gutowski, F. McCormick and K. C. Holmes

Journal:

Philosophical Transactions Biological Sciences

Year:

1992

Language:

english

File:

PDF, 1.20 MB

english, 1992

4

Identification and Characterization of Unique Proline-rich Peptides Binding to the Mitochondrial Fission Protein hFis1

Serasinghe, Madhavika N., Seneviratne, A. M. P. B., Smrcka, Alan V., Yoon, Yisang

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 3.06 MB

english, 2010

5

G Protein Signaling Volume 237 || Methods for Measuring RGS Protein Phosphorylation by G Protein-Regulated Kinases

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

6

[Methods in Enzymology] G Protein Pathways, Part B: G Proteins and their Regulators Volume 344 || Discovery of Ligands for βγ Subunits from Phage-Displayed Peptide Libraries

Smrcka, Alan V.

Year:

2002

Language:

english

File:

PDF, 1.10 MB

english, 2002

7

Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production

de Rubio, Rafael Gil, Ransom, Richard F., Malik, Sundeep, Yule, David I., Anantharam, Arun, Smrcka, Alan V.

Journal:

Science Signaling

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

8

Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling

Joe B. Blumer, Alan V. Smrcka, Stephen M. Lanier

Journal:

Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 1.25 MB

english, 2007

9

Inhibition of G protein βγ subunit signaling abrogates nephritis in lupus prone mice

Rangel-Moreno, Javier, To, Jesi Y., Owen, Teresa, Goldman, Bruce I., Smrcka, Alan V., Anolik, Jennifer H.

Journal:

Arthritis & Rheumatology

Year:

2016

Language:

english

File:

PDF, 2.28 MB

english, 2016

10

G Protein Signaling Volume 237 || Assays of Recombinant Adenylyl Cyclases Expressed in Sf9 Cells

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

11

G Protein Signaling Volume 237 || Assay for G Protein-Dependent Activation of Phospholipase C β Using Purified Protein Components

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

12

G Protein Signaling Volume 237 || In Vivo Adenoviral-Mediated Gene Transfer of the βARKct to Study the Role of Gβγ in Arterial Restenosis

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

13

Gedunin- and Khivorin-Derivatives Are Small-Molecule Partial Agonists for Adhesion G Protein-Coupled Receptors GPR56/ADGRG1 and GPR114/ADGRG5

Stoveken, Hannah M., Larsen, Scott D., Smrcka, Alan V., Tall, Gregory G.

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

14

Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease

Squires, Katherine E., Montañez-Miranda, Carolina, Pandya, Rushika R., Torres, Matthew P., Hepler, John R., Smrcka, Alan V.

Journal:

Pharmacological Reviews

Year:

2018

Language:

english

File:

PDF, 1.71 MB

english, 2018

15

G Protein Signaling Volume 237 || Detection of G Protein-Coupled Receptors by Immunofluorescence Microscopy

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

16

Directional Sensing Requires Gβγ-Mediated PAK1 and PIXα-Dependent Activation of Cdc42

Zhong Li, Michael Hannigan, Zhicheng Mo, Bo Liu, Wei Lu, Yue Wu, Alan V. Smrcka, Guanqing Wu, Lin Li, Mingyao Liu, Chi-Kuang Huang, Dianqing Wu

Journal:

Year:

2003

Language:

english

File:

PDF, 547 KB

english, 2003

17

G Protein Signaling Volume 237 || Selective Inhibition of G Protein-Mediated Pathways Using RGS Domains

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 245 KB

english, 2003

18

Taking the heart failure battle inside the cell: Small molecule targeting of Gβγ subunits

Fadia A. Kamal, Alan V. Smrcka, Burns C. Blaxall

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 247 KB

english, 2011

19

A Chemical Biology Approach Demonstrates G Protein βγ Subunits Are Sufficient to Mediate Directional Neutrophil Chemotaxis

Surve, Chinmay R., Lehmann, David, Smrcka, Alan V.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

20

G Protein Signaling Volume 237 || Green Fluorescent Protein-Tagged β-Arrestin Translocation as a Measure of G Protein-Coupled Receptor Activation

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

21

Thrombin Promotes Sustained Signaling and Inflammatory Gene Expression through the CDC25 and Ras-associating Domains of Phospholipase Cϵ

Dusaban, Stephanie S., Kunkel, Maya T., Smrcka, Alan V., Brown, Joan Heller

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.51 MB

english, 2015

22

Conformational flexibility and binding interactions of the G protein βγ heterodimer

Min-Sun Park, Alan V. Smrcka, Harry A. Stern

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2011

Language:

english

File:

PDF, 739 KB

english, 2011

23

G Protein β 5 Subunit Interactions with α Subunits and Effectors †

Yoshikawa, Daniel M., Hatwar, Mamata, Smrcka, Alan V.

Journal:

Year:

2000

Language:

english

File:

PDF, 185 KB

english, 2000

24

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans

Dzhura, Igor, Chepurny, Oleg G., Leech, Colin A., Roe, Michael W., Dzhura, Elvira, Xu, Xin, Lu, Youming, Schwede, Frank, Genieser, Hans-G., Smrcka, Alan V., Holz, George G.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.10 MB

english, 2011

25

Purification and characterization of large and small subunits of ribulose 1,5-bisphosphate carboxylase expressed separately in Escherichia coli

Alan V. Smrcka, Robert T. Ramage, Hans J. Bohnert, Richard G. Jensen

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 1.77 MB

english, 1991

26

G Protein Signaling Volume 237 || Analysis of G Protein-Mediated Activation of Phospholipase C in Cultured Cells

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 84 KB

english, 2003

27

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] C26. REGULATORS OF THE LUNG ENDOTHELIAL BARRIER - Critical Role Of Phospholipase C Epsilon In Lipopolysaccharide-Induced Lung Inflammation

Bijli, Kaiser M., Fazal, Fabeha, Smrcka, Alan, Rahman, Arshad

Year:

2011

Language:

english

File:

PDF, 17 KB

english, 2011

28

Modulation of the tight binding of carboxyarabinitol 1,5-bisphosphate to the large subunit of ribulose 1,5-bisphosphate carboxylase/oxygenase

Alan V. Smrcka, Hans J. Bohnert, Richard G. Jensen

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 701 KB

english, 1991

29

Phospholipase C-ε signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury

Bijli, Kaiser M., Fazal, Fabeha, Slavin, Spencer A., Leonard, Antony, Grose, Valerie, Alexander, William B., Smrcka, Alan V., Rahman, Arshad

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

30

Activation of Phospholipase C Î² by GÎ²Î³ and GÎ±q Involves C-Terminal Rearrangement to Release Autoinhibition

Fisher, Isaac J., Jenkins, Meredith L., Tall, Gregory G., Burke, John E., Smrcka, Alan V.

Journal:

Year:

2020

File:

PDF, 2.69 MB

2020

31

Regulation of phospholipase C by G proteins

Sternweis, Paul C., Smrcka, Alan V.

Journal:

Trends in Biochemical Sciences

Year:

1992

Language:

english

File:

PDF, 713 KB

english, 1992

32

G Protein Signaling Volume 237 || Expression and Purification of Soluble Adenylyl Cyclase from Escherichia coli

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

33

Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment

Kim, Kyun-Do, Bae, Seyeon, Capece, Tara, Nedelkovska, Hristina, de Rubio, Rafael G., Smrcka, Alan V., Jun, Chang-Duk, Jung, Woojin, Park, Byeonghak, Kim, Tae-il, Kim, Minsoo

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

34

G Protein Signaling Volume 237 || Assay of G Protein-Coupled Receptor Activation of G Proteins in Native Cell Membranes Using [35S]GTPγS Binding

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

35

G Protein Signaling Volume 237 || Analysis of the Coupling of G12/13 to G Protein-Coupled Receptors Using a Luciferase Reporter Assay

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 89 KB

english, 2003

36

G Protein Signaling Volume 237 || Purification of Phospholipase C β and Phospholipase C ε from Sf9 Cells

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

37

The Role of G Protein Methylation in the Function of a Geranylgeranylated βγ Isoform †

Parish, Craig A., Smrcka, Alan V., Rando, Robert R.

Journal:

Year:

1996

Language:

english

File:

PDF, 302 KB

english, 1996

38

Fluorescence detection of cationic amyloid fibrils in human semen

Easterhoff, David, DiMaio, John T.M., Liyanage, Wathsala, Lo, Chi-Wen, Bae, Woori, Doran, Todd M., Smrcka, Alan, Nilsson, Bradley L., Dewhurst, Stephen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 786 KB

english, 2013

39

G Protein Signaling Volume 237 ||

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 1.85 MB

english, 2003

40

G Protein Signaling Volume 237 || Measurement of G Protein-Coupled Receptor-Stimulated Phospholipase D Activity in Intact Cells

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

41

Purification and Characterization of Recombinant G16αFrom Sf9 Cells: Activation of Purified Phospholipase C Isozymes by G-Protein α Subunits

Tohru Kozasa, John R. Hepler, Alan V. Smrcka, Melvin I. Simon, Sue Goo Rhee, Paul C. Sternweis and Alfred G. Gilman

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 932 KB

english, 1993

42

Evaluating Docking Methods for Prediction of Binding Affinities of Small Molecules to the G Protein βγ Subunits

Park, Min-Sun, Dessal, Axel L., Smrcka, Alan V., Stern, Harry A.

Journal:

Journal of Chemical Information and Modeling

Year:

2009

Language:

english

File:

PDF, 1.49 MB

english, 2009

43

Genetic Alteration of Phospholipase C β 3 Expression Modulates Behavioral and Cellular Responses to μ Opioids

Wei Xie, Gary M. Samoriski, Jay P. McLaughlin, Valerie A. Romoser, Alan Smrcka, Patricia M. Hinkle, Jean M. Bidlack, Robert A. Gross, Huiping Jiang and Dianqing Wu

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.58 MB

english, 1999

44

Identification of a Phospholipase C β2Region that Interacts with Gβ γ

Yanan Kuang, Yaqing Wu, Alan Smrcka, Huiping Jiang and Dianqing Wu

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 860 KB

english, 1996

45

Identification of a Region at the N-Terminus of Phospholipase C-β3 That Interacts with G Protein βγ Subunits †

Barr, Alastair J., Ali, Hydar, Haribabu, Bodduluri, Snyderman, Ralph, Smrcka, Alan V.

Journal:

Year:

2000

Language:

english

File:

PDF, 121 KB

english, 2000

46

G Protein Signaling Volume 237 || Purification of Recombinant G Protein α Subunits from Escherichia coli

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 149 KB

english, 2003

47

NMR Analysis of G-protein βγ Subunit Complexes Reveals a Dynamic Gα-Gβγ Subunit Interface and Multiple Protein Recognition Modes

Alan V. Smrcka, Nessim Kichik, Teresa Tarragó, Michael Burroughs, Min-Sun Park, Nathan K. Itoga, Harry A. Stern, Barry M. Willardson, Ernest Giralt and Melvin I. Simon

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

48

G Protein Signaling Volume 237 || Ribozymes as Tools for Suppression of G Protein γ Subunits

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 130 KB

english, 2003

49

Compartmentalized cyclic nucleotides have opposing effects on regulation of hypertrophic phospholipase Cε signaling in cardiac myocytes

Nash, Craig A., Brown, Loren M., Malik, Sundeep, Cheng, Xiaodong, Smrcka, Alan V.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2018

Language:

english

File:

PDF, 5.02 MB

english, 2018

50

G Protein Signaling Volume 237 || The Use of Green Fluorescent Proteins to View Association Between Phospholipase Cβ and G Protein Subunits in Cells

Smrcka, Alan V.

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

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